GEM-based computational modeling for exploring metabolic interactions in a microbial community.

ABSTRACT: Microbial communities play fundamental roles in every complex ecosystem, such as soil, sea and the human body. The stability and diversity of the microbial community depend precisely on the composition of the microbiota. Any change in the composition of these communities affects microbial functions. An important goal of studying the interactions between species is to understand the behavior of microbes and their responses to perturbations. These interactions among species are mediated by the exchange of metabolites within microbial communities. We developed a computational model for the microbial community that has a separate compartment for exchanging metabolites. This model can predict possible metabolites that cause competition, commensalism, and mutual interactions between species with

SUBMITTER: Mirzaei S 

PROVIDER: S-EPMC11218945 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature