Connecting the Dots: Exploring the Interplay Between Preeclampsia and Peripartum Cardiomyopathy.

ABSTRACT: Preeclampsia and peripartum cardiomyopathy (PPCM) are significant obstetric problems that can arise during or after pregnancy. Both are known to be causes of maternal mortality and morbidity. Several recent studies have suggested a link between preeclampsia and the pathophysiology of PPCM. However, the common thread that connects the two has yet to be thoroughly and fully articulated. Here, we investigate the complex dynamics of preeclampsia and PPCM in this review. Our analysis focuses mainly on inflammatory and immunological responses, endothelial dysfunction as a shared pathway, and potential genetic predisposition to both diseases. To begin, we will look at how excessive inflammatory and immunological responses can lead to clinical symptoms of both illnesses, emphasizing the role of pr

SUBMITTER: Gumilar KE 

PROVIDER: S-EPMC11219213 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature