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Sex differences in the association between vitamin D and prediabetes in adults: A cross-sectional study.


ABSTRACT:

Background/objectives

Vitamin D status has been shown to be associated with prediabetes risk. However, epidemiologic evidence on whether sex modulates the association between vitamin D and prediabetes is limited. The present study investigated sex-specific associations between vitamin D and prediabetes.

Subjects/methods

The Kuwait Wellbeing Study, a population-based cross-sectional study, enrolled nondiabetic adults. Prediabetes was defined as 5.7 ≤ HbA1c% ≤6.4; 25-hydroxyvitamin D (25(OH)D) was measured in venous blood and analyzed as a continuous, dichotomous (deficiency: <50 nmol/L vs. insufficiency/sufficiency ≥50 nmol/L), and categorical (tertiles) variable. Associations were evaluated by estimating adjusted prevalence ratios (aPRs) and 95% confidence intervals (CIs), w

SUBMITTER: Ziyab AH 

PROVIDER: S-EPMC11219834 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature