Predicting conversion from mild cognitive impairment to Alzheimer's disease: a multimodal approach.

ABSTRACT: Successively predicting whether mild cognitive impairment patients will progress to Alzheimer's disease is of significant clinical relevance. This ability may provide information that can be leveraged by emerging intervention approaches and thus mitigate some of the negative effects of the disease. Neuroimaging biomarkers have gained some attention in recent years and may be useful in predicting the conversion of mild cognitive impairment to Alzheimer's disease. We implemented a novel multi-modal approach that allowed us to evaluate the potential of different imaging modalities, both alone and in different degrees of combinations, in predicting the conversion to Alzheimer's disease of mild cognitive impairment patients. We applied this approach to the imaging data from the Alzheimer's Dise

SUBMITTER: Agostinho D 

PROVIDER: S-EPMC11220508 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature