Recurrence and tumor-related death after resection of hepatocellular carcinoma in patients with metabolic syndrome.

ABSTRACT:

Background & aims

Metabolic syndrome (MS) is a growing epidemic and a risk factor for the development of hepatocellular carcinoma (HCC). This study investigated the long-term outcomes of liver resection (LR) for HCC in patients with MS. Rates, timing, patterns, and treatment of recurrences were investigated, and cancer-specific survivals were assessed.

Methods

Between 2001 and 2021, data from 24 clinical centers were collected. Overall survival (OS), recurrence-free survival (RFS), and cancer-specific survival were analyzed as well as recurrence patterns and treatment. The analysis was conducted using a competing-risk framework. The trajectory of the risk of recurrence over time was applied to a competing risk analysis. For post-recurrence survival, death resulting from tumo

SUBMITTER: Berardi G 

PROVIDER: S-EPMC11220535 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature