Biliary intervention rates during neoadjuvant therapy for adenocarcinoma of the pancreatic head.

ABSTRACT:

Background

Neoadjuvant therapy prior to resection of adenocarcinoma of the pancreatic head increases time to surgery and thus the possibility of biliary complications. We hypothesized that biliary complications during neoadjuvant therapy negatively impact clinical outcomes.

Methods

We completed a retrospective study of a cohort of borderline resectable patients consistently treated with neoadjuvant therapy from May 2014 through March 2019. Biliary complications were defined as new-onset biliary obstruction, existing stent failure, cholecystitis, and cholangitis.

Results

Of 59 patients that met inclusion criteria, 34 (57.6%) went on to resection. Biliary complications affected 16 patients (27%); 8 (50%) of these patients went on to surgical resection. Of those 43 patie

SUBMITTER: Kirkpatrick S 

PROVIDER: S-EPMC11220575 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature