Heat-related illness and dementia: a study integrating epidemiological and experimental evidence.

ABSTRACT:

Background

Heat-related illness (HRI) is commonly considered an acute condition, and its potential long-term consequences are not well understood. We conducted a population-based cohort study and an animal experiment to evaluate whether HRI is associated with dementia later in life.

Methods

The Taiwan National Health Insurance Research Database was used in the epidemiological study. We identified newly diagnosed HRI patients between 2001 and 2015, but excluded those with any pre-existing dementia, as the study cohort. Through matching by age, sex, and the index date with the study cohort, we selected individuals without HRI and without any pre-existing dementia as a comparison cohort at a 1:4 ratio. We followed each cohort member until the end of 2018 and compared the risk b

SUBMITTER: Kuo WY 

PROVIDER: S-EPMC11221187 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature