Occupational exposure to organic solvents and risk of bladder cancer.

ABSTRACT:

Background

Bladder cancer has been linked to several occupations that involve the use of solvents, including those used in the dry-cleaning industry.

Objectives

We evaluated exposure to solvents and risk of bladder cancer in 1182 incident cases and 1408 controls from a population-based study.

Methods

Exposure to solvents was quantitatively assessed using a job-exposure matrix (CANJEM). Exposure to benzene, toluene and xylene often co-occur. Therefore, we created two additional sets of metrics for combined benzene, toluene and xylene (BTX) exposure: (1) CANJEM-based BTX metrics and (2) hybrid BTX metrics, using an approach that integrates the CANJEM-based BTX metrics together with lifetime occupational histories and exposure-oriented modules that captured within-job, r

SUBMITTER: Xie S 

PROVIDER: S-EPMC11222140 | biostudies-literature | 2024 May

REPOSITORIES: biostudies-literature