The cooperative regulatory effect of the miRNA-130 family on milk fat metabolism in dairy cows.

ABSTRACT:

Objective

There is a strong relationship between the content of beneficial fatty acids in milk and milk fat metabolic activity in the mammary gland. To improve milk quality, it is therefore necessary to study fatty acid metabolism in bovine mammary gland tissue. In adipose tissue, peroxisome proliferator-activated receptor gamma (PPARG), the core transcription factor, regulates the fatty acid metabolism gene network and determines fatty acid deposition. However, its regulatory effects on mammary gland fatty acid metabolism during lactation have rarely been reported.

Methods

Transcriptome sequencing was performed during the prelactation period and the peak lactation period to examine mRNA expression. The significant upregulation of PPARG drew our attention and led us to condu

SUBMITTER: Li X 

PROVIDER: S-EPMC11222843 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature