Long-term Outcomes of Adjunctive Lung Resection for Nontuberculous Mycobacteria Pulmonary Disease.

ABSTRACT:

Background

Adjunctive lung resection is recommended for select patients with nontuberculous mycobacteria (NTM) pulmonary disease (PD). However, data are limited on long-term recurrence rates in patients infected with major pathogens, including Mycobacterium avium complex (MAC) and Mycobacterium abscessus (MABC).

Methods

In this prospective observational study, we retrospectively analyzed data from 125 patients with MAC-PD (n = 90) or MABC-PD (n = 35) who underwent adjunctive lung resection. We evaluated microbiological response, postoperative complications, recurrence, and all-cause mortality over a median 80-month follow-up.

Results

Persistent culture positivity (64%) was the most common indication for surgery, followed by hemoptysis, recurrent pneumoni

SUBMITTER: Kang N 

PROVIDER: S-EPMC11222975 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature