Pancreatic Cancer Surveillance and Survival of High-Risk Individuals.

ABSTRACT:

Importance

Pancreatic ductal adenocarcinoma (PDAC) is a deadly disease with increasing incidence. The majority of PDACs are incurable at presentation, but population-based screening is not recommended. Surveillance of high-risk individuals for PDAC may lead to early detection, but the survival benefit is unproven.

Objective

To compare the survival of patients with surveillance-detected PDAC with US national data.

Design, setting, and participants

This comparative cohort study was conducted in multiple US academic medical centers participating in the Cancer of the Pancreas Screening program, which screens high-risk individuals with a familial or genetic predisposition for PDAC. The comparison cohort comprised patients with PDAC matched for age, sex, and year of diagnos

SUBMITTER: Blackford AL 

PROVIDER: S-EPMC11223057 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature