Quartz Crystal Microbalance Frequency Response to Discrete Adsorbates in Liquids.

ABSTRACT: Quartz crystal microbalance with dissipation monitoring (QCM-D) has become a major tool enabling accurate investigation of the adsorption kinetics of nanometric objects such as DNA fragments, polypeptides, proteins, viruses, liposomes, polymer, and metal nanoparticles. However, in liquids, a quantitative analysis of the experimental results is often intricate because of the complex interplay of hydrodynamic and adhesion forces varying with the physicochemical properties of adsorbates and functionalized QCM-D sensors. In the present paper, we dissect the role of hydrodynamics for the analytically tractable case of stiff contact, whereas the adsorbed rigid particles oscillate with the resonator without rotation. Under the assumption of the low surface coverage, we theoretically study the exc

SUBMITTER: Leshansky AM 

PROVIDER: S-EPMC11223097 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature