Implementing ABCD study^Ⓡ MRI sequences for multi-site cohort studies: Practical guide to necessary steps, preprocessing methods, and challenges.

ABSTRACT: Large multi-site studies that combine magnetic resonance imaging (MRI) data across research sites present exceptional opportunities to advance neuroscience research. However, scanner or site variability and non-standardised image acquisition protocols, data processing and analysis pipelines can adversely affect the reliability and repeatability of MRI derived brain measures. We implemented a standardised MRI protocol based on that used in the Adolescent Brain Cognition Development (ABCD)^Ⓡ study in two sites, and across four MRI scanners. Twice repeated measurements of a single healthy volunteer were obtained in two sites and in four 3T MRI scanners (vendors: Siemens, Philips, and GE). Imaging data included anatomical scans (T1 weighted, T2 weighted), diffusion weighted imaging (

SUBMITTER: Bano W 

PROVIDER: S-EPMC11223117 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature