House dust mite allergen avoidance strategies for the treatment of allergic asthma: A hypothesis-generating meta-analysis.

ABSTRACT:

Background

This study continues the review by Gøtzsche and Johansen (Cochrane Database of Systematic Reviews, 2008, Art. No: CD001187), aiming to systematically generate hypotheses on the effectiveness of (sub)strategies for house dust mite allergen avoidance in the treatment of allergic asthma.

Methods

We used the trials previously analysed by Gøtzsche and Johansen and searched recently published studies. Data on asthma symptom scores (ASS), ACQ, number of improved patients, AQLQ-scores, medication use, FEV₁%, PC₂₀, and FeNO levels were analysed. The effectiveness of strategies was assessed using Metafor in R.

Results

Thirty-five trials involving 2419 patients were included in the final study. The patient-reported outcome number of patients with

SUBMITTER: van Boven FE 

PROVIDER: S-EPMC11223119 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature