Detection of pan-azole resistant Aspergillus fumigatus in horticulture and a composting facility in Belgium.

ABSTRACT: Azole resistance in Aspergillus fumigatus (ARAf) is becoming a worldwide health threat due to increasing occurrence in the environment. However, environmental surveillance programs are not commonly in place and are lacking in Belgium. Since no data on the occurrence of ARAf and the presence of hotspots for the selection of azole resistance is available in Belgium, a first study on the prevalence of ARAf in the environment was conducted. A total of 232 air and compost or soil samples were taken from two composting facilities, and from horticultural and agricultural crops. The azole susceptibility pattern was determined using the EUCAST method (E. Def. 9.4), and the cyp51A gene and its promotor region were sequenced in A. fumigatus isolates with phenotypic azole resistance. Six pan-azole-res

SUBMITTER: Debergh H 

PROVIDER: S-EPMC11223581 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature