Effects of Different Scleral Photo-Crosslinking Modalities on Scleral Stiffness and Hydration.

ABSTRACT:

Purpose

The purpose of this study was to evaluate the biomechanical and hydration differences in scleral tissue after two modalities of collagen cross-linking.

Methods

Scleral tissue from 40 adult white rabbit eyes was crosslinked by application of 0.1% Rose Bengal solution followed by 80 J/cm2 green light irradiation (RGX) or by application of 0.1% riboflavin solution followed by 5.4 J/cm2 ultraviolet A irradiation (UVX). Posterior scleral strips were excised from treated and untreated sclera for tensile and hydration-tensile tests. For tensile tests, the strips were subjected to uniaxial extension after excision. For hydration-tensile tests, the strips were dehydrated, rehydrated, and then tested. Young's modulus at 8% strain and swelling rate were estimated. ANOVAs were u

SUBMITTER: Villegas L 

PROVIDER: S-EPMC11223619 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature