Pred-O3, a web server to predict molecules, olfactory receptors and odor relationships.

ABSTRACT: The sense of smell is a biological process involving volatile molecules that interact with proteins called olfactory receptors to transmit a nervous message that allows the recognition of a perceived odor. However, the relationships between odorant molecules, olfactory receptors and odors (O3) are far from being well understood due to the combinatorial olfactory codes and large family of olfactory receptors. This is the reason why, based on 5802 odorant molecules and their annotations to 863 olfactory receptors (human) and 7029 odors and flavors annotations, a web server called Pred-O3 has been designed to provide insights into olfaction. Predictive models based on Artificial Intelligence have been developed allowing to suggest olfactory receptors and odors associated with a new molecule.

SUBMITTER: Ollitrault G 

PROVIDER: S-EPMC11223793 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature