Racial and ethnic associations with comprehensive cancer center access and clinical trial enrollment for acute leukemia.

ABSTRACT:

Background

Clinical trial participation at Comprehensive Cancer Centers (CCC) is inequitable for minoritized racial and ethnic groups with acute leukemia. CCCs care for a high proportion of adults with acute leukemia. It is unclear if participation inequities are due to CCC access, post-access enrollment, or both.

Methods

We conducted a retrospective cohort study of adults with acute leukemia (2010-2019) residing within Massachusetts, the designated catchment area of the Dana-Farber/Harvard Cancer Center (DF/HCC). Individuals were categorized as non-Hispanic Asian (NHA), Black (NHB), White (NHW), Hispanic White (HW), or Other. Decomposition analyses assessed covariate contributions to disparities in (1) access to DF/HCC care and (2) post-access enrollment.

Results

Of

SUBMITTER: Hantel A 

PROVIDER: S-EPMC11223832 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature