Use of cancer-directed therapy at the end of life among adolescents and young adults.

ABSTRACT:

Background

Adolescents and young adults frequently receive chemotherapy near death. We know less about the use of targeted agents and immunotherapy or trends over time.

Methods

We conducted a retrospective cohort study of 1836 adolescents and young adults with cancer who died between 2009 and 2019 after receiving care at 1 of 3 sites (Dana-Farber Cancer Institute, Kaiser Permanente Northern California, and Kaiser Permanente Southern California). We reviewed electronic health data and medical records to examine use of cancer-directed therapy in the last 90 days of life, including chemotherapy, targeted therapy, immunotherapy, and investigational drugs.

Results

Over the study period, 35% of adolescents and young adults received chemotherapy in the last 90 days of life;

SUBMITTER: Mack JW 

PROVIDER: S-EPMC11223859 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature