EANM consensus document on the use of [¹⁸F]FDG PET/CT in fever and inflammation of unknown origin.

ABSTRACT:

Purpose

Patients with fever and inflammation of unknown origin (FUO/IUO) are clinically challenging due to variable clinical presentations with nonspecific symptoms and many differential diagnoses. Positron emission tomography/computed tomography (PET/CT) with 2-deoxy-2-[¹⁸F]fluoro-D-glucose ([¹⁸F]FDG) is increasingly used in FUO and IUO, but the optimal diagnostic strategy remains controversial. This consensus document aims to assist clinicians and nuclear medicine specialists in the appropriate use of [¹⁸F]FDG-PET/CT in FUO and IUO based on current evidence.

Methods

A working group created by the EANM infection and inflammation committee performed a systematic literature search based on PICOs with "patients with FUO/IUO" as population, "[

SUBMITTER: Hess S 

PROVIDER: S-EPMC11224117 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature