Construction of lignan glycosides biosynthetic network in Escherichia coli using mutltienzyme modules.

ABSTRACT:

Background

Due to the complexity of the metabolic pathway network of active ingredients, precise targeted synthesis of any active ingredient on a synthetic network is a huge challenge. Based on a complete analysis of the active ingredient pathway in a species, this goal can be achieved by elucidating the functional differences of each enzyme in the pathway and achieving this goal through different combinations. Lignans are a class of phytoestrogens that are present abundantly in plants and play a role in various physiological activities of plants due to their structural diversity. In addition, lignans offer various medicinal benefits to humans. Despite their value, the low concentration of lignans in plants limits their extraction and utilization. Recently, synthetic biology approa

SUBMITTER: Qiao Y 

PROVIDER: S-EPMC11225284 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature