ScMultiome analysis identifies a single caudal hindbrain compartment in the developing zebrafish nervous system.

ABSTRACT:

Background

A key step in nervous system development involves the coordinated control of neural progenitor specification and positioning. A long-standing model for the vertebrate CNS postulates that transient anatomical compartments - known as neuromeres - function to position neural progenitors along the embryonic anteroposterior neuraxis. Such neuromeres are apparent in the embryonic hindbrain - that contains six rhombomeres with morphologically apparent boundaries - but other neuromeres lack clear morphological boundaries and have instead been defined by different criteria, such as differences in gene expression patterns and the outcomes of transplantation experiments. Accordingly, the caudal hindbrain (CHB) posterior to rhombomere (r) 6 has been variably proposed to contain from

SUBMITTER: Warns J 

PROVIDER: S-EPMC11225431 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature