Crystal structure elucidation of a geminal and vicinal bis(trifluoromethanesulfonate) ester.

ABSTRACT: Geminal and vicinal bis(trifluoromethanesulfonate) esters are highly reactive alkylene synthons used as potent electrophiles in the macrocyclization of imidazoles and the transformation of bypyridines to diquat derivatives via nucleophilic substitution reactions. Herein we report the crystal structures of methylene (C₃H₂F₆O₆S₂) and ethylene bis(trifluoromethanesulfonate) (C₄H₄F₆O₆S₂), the first examples of a geminal and vicinal bis(trifluoromethanesulfonate) ester characterized by single-crystal X-ray diffraction (SC-XRD). With melting points slightly below ambient temperature, both reported bis(trifluoromethanesulfonate)s are air- and moisture-sensitive oils and were crystallized

SUBMITTER: Pickl T 

PROVIDER: S-EPMC11225611 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature