Obesity is associated with lower levels of negative emotions in polycystic ovary syndrome in clinical and animal studies.

ABSTRACT:

Background

Polycystic ovary syndrome (PCOS) is one of the most common endocrine and metabolic disorders in women of reproductive age. It is frequently comorbid with obesity and negative emotions. Currently, there are few reports on the relationship between obesity and negative emotions in patients with PCOS. Here we performed both basic and clinical studies to study the relationship between obesity and negative emotions in PCOS.

Methods

We performed a cross-sectional study including 608 patients with PCOS and 184 healthy participants to assess the mental health status of people with different body mass indices (BMI). Self-rated anxiety, depression, and perceived stress scales were used for subjective mood evaluations. Rat PCOS models fed 45 and 60% high-fat diets were used t

SUBMITTER: Zhang H 

PROVIDER: S-EPMC11225633 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature