Patient-reported physical well-being predicts good long-term survival of hematopoietic stem cell transplantation.

ABSTRACT:

Aim

This study aimed to explore the association between patient-reported items at different time points after hematopoietic stem cell transplantation (HSCT) and long-term survival.

Methods

We conducted a study with 144 allogeneic HSCT patients, following them for 5 years post-transplantation. Data from the Functional Assessment of Cancer Therapy-Bone Marrow Transplant (FACT-BMT) questionnaire were collected before transplantation and at 1, 3, 6, 12, 18, 36, and 60 months after transplantation. Demographic characteristics and survival status were also assessed.

Results

Among the 144 cases, the 5-year overall survival (OS), progression-free survival (PFS), non-relapse mortality (NRM), and graft-versus-host disease-free (GRFS) rates were 65%, 48%, 17%, and 36% respective

SUBMITTER: Lu Y 

PROVIDER: S-EPMC11225646 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature