Identification of Southeast Asian Anopheles mosquito species using MALDI-TOF mass spectrometry.

ABSTRACT: Malaria elimination in Southeast Asia remains a challenge, underscoring the importance of accurately identifying malaria mosquitoes to understand transmission dynamics and improve vector control. Traditional methods such as morphological identification require extensive training and cannot distinguish between sibling species, while molecular approaches are costly for extensive screening. Matrix-assisted laser desorption and ionization time-of-flight mass spectrometry (MALDI-TOF MS) has emerged as a rapid and cost-effective tool for Anopheles species identification, yet its current use is limited to few specialized laboratories. This study aimed to develop and validate an online reference database for MALDI-TOF MS identification of Southeast Asian Anopheles species. The database, constructe

SUBMITTER: Chaumeau V 

PROVIDER: S-EPMC11226003 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature