Newborn screening analytes and structural birth defects among 27,000 newborns.

ABSTRACT:

Background

Emerging evidence suggests newborn screening analytes may yield insights into the etiologies of birth defects, yet no effort has evaluated associations between a range of newborn screening analytes and birth defects.

Methods

This population-based study pooled statewide data on birth defects, birth certificates, and newborn screening analytes from Texas occurring between January 1, 2007 and December 31, 2009. Associations between a panel of thirty-six newborn screening analytes, collected by the statewide Texas Newborn Screening Program, and the presence of a birth defect, defined as at least one of 39 birth defects diagnoses recorded by the Texas Birth Defects Registry, were assessed using regression analysis.

Findings

Of the 27,643 births identified, 20,20

SUBMITTER: Lupo PJ 

PROVIDER: S-EPMC11226011 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature