Chromosome segregation during spermatogenesis occurs through a unique center-kinetic mechanism in holocentric moth species.

ABSTRACT: Precise regulation of chromosome dynamics in the germline is essential for reproductive success across species. Yet, the mechanisms underlying meiotic chromosomal events such as homolog pairing and chromosome segregation are not fully understood in many species. Here, we employ Oligopaint DNA FISH to investigate mechanisms of meiotic homolog pairing and chromosome segregation in the holocentric pantry moth, Plodia interpunctella, and compare our findings to new and previous studies in the silkworm moth, Bombyx mori, which diverged from P. interpunctella over 100 million years ago. We find that pairing in both Bombyx and Plodia spermatogenesis is initiated at gene-rich chromosome ends. Additionally, both species form rod shaped cruciform-like bivalents at metaphase I. However, unlike the te

SUBMITTER: Hockens C 

PROVIDER: S-EPMC11226059 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature