Investigation of fast and efficient lossless compression algorithms for macromolecular crystallography experiments.

ABSTRACT: Structural biology experiments benefit significantly from state-of-the-art synchrotron data collection. One can acquire macromolecular crystallography (MX) diffraction data on large-area photon-counting pixel-array detectors at framing rates exceeding 1000 frames per second, using 200 Gbps network connectivity, or higher when available. In extreme cases this represents a raw data throughput of about 25 GB s^-1, which is nearly impossible to deliver at reasonable cost without compression. Our field has used lossless compression for decades to make such data collection manageable. Many MX beamlines are now fitted with DECTRIS Eiger detectors, all of which are delivered with optimized compression algorithms by default, and they perform well with current framing rates and typical dif

SUBMITTER: Bernstein HJ 

PROVIDER: S-EPMC11226158 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature