Laparoscopy is non-inferior to open surgery for rectal cancer: A systematic review and meta-analysis.

ABSTRACT:

Background

Laparoscopic surgery has been endorsed by clinical guidelines for colon cancer, but not for rectal cancer on account of unapproved oncologic equivalence with open surgery.

Aims

We started this largest-to-date meta-analysis to comprehensively evaluate the safety and efficacy of laparoscopy in the treatment of rectal cancer compared with open surgery.

Materials & methods

Both randomized and nonrandomized controlled trials comparing laparoscopic proctectomy and open surgery between January 1990 and March 2020 were searched in PubMed, Cochrane Library and Embase Databases (PROSPERO registration number CRD42020211718). The data of intraoperative, pathological, postoperative and survival outcomes were compared between two groups.

Results

Twenty RCTs and 93

SUBMITTER: Ma L 

PROVIDER: S-EPMC11226727 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature