Very long-term outcomes of pediatric patients treated for optic pathway gliomas: A longitudinal cohort study.

ABSTRACT:

Background

Optic pathway gliomas (OPGs) represent 5% of childhood brain tumors. Successive relapses lead to multiple treatments exposing to late complications.

Methods

We included patients treated at Gustave Roussy (GR) between January 1980 and December 2015 for OPG, before 18 years old and alive at 5 years from diagnosis. Mortality and physical health conditions data were extracted from medical data files and updated, thanks to the GR long-term follow-up program and French national mortality registry for patients included in the French Childhood Cancer Survivor Study.

Results

We included 182 5-year OPG-childhood survivors in the analysis (sex ratio M/F 0.8, 35% with neurofibromatosis type 1 [NF1]). With a median follow-up of 17.2 years (range = 5-41), we registered 8

SUBMITTER: Morin A 

PROVIDER: S-EPMC11226872 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature