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A systematic review of subclinical hyperthyroidism guidelines: a remarkable range of recommendations.


ABSTRACT:

Background

Subclinical thyroid diseases are often the subject of debate concerning their clinical significance, the appropriateness of diagnostic testing, and possible treatment. This systematic review addresses the variation in international guidelines for subclinical hyperthyroidism, focusing on diagnostic workup, treatment, and follow-up recommendations.

Methods

Following the PRISMA guidelines, we searched PubMed, Embase, and guideline-specific databases and included clinical practice guidelines with recommendations on subclinical hyperthyroidism. Guideline recommendations were extracted, and quality assessment was performed using selected questions of the Appraisal of Guidelines for Research & Evaluation (AGREE) II instrument.

Results

Of the 2624 records screened,

SUBMITTER: Ursem SR 

PROVIDER: S-EPMC11227059 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature