Biomarker Testing Disparities in Metastatic Colorectal Cancer.

ABSTRACT:

Importance

Among patients with metastatic colorectal cancer (mCRC), data are limited on disparate biomarker testing and its association with clinical outcomes on a national scale.

Objective

To evaluate the socioeconomic and demographic inequities in microsatellite instability (MSI) and KRAS biomarker testing among patients with mCRC and to explore the association of testing with overall survival (OS).

Design, setting, and participants

This cohort study, conducted between November 2022 and March 2024, included patients who were diagnosed with mCRC between January 1, 2010, and December 31, 2017. The study obtained data from the National Cancer Database, a hospital-based cancer registry in the US. Patients with mCRC and available information on biomarker testing were inc

SUBMITTER: Sabbagh S 

PROVIDER: S-EPMC11227072 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature