Association between atherogenic index of plasma and gestational diabetes mellitus: a prospective cohort study based on the Korean population.

ABSTRACT:

Background

Atherogenic index of plasma (AIP) is a non-traditional lipid parameter that can reflect the burden of atherosclerosis. A lipid profile resembling atherosclerosis emerged during pregnancy. Although lipid metabolism is pivotal in diabetes pathogenesis, there is no evidence linking AIP to gestational diabetes mellitus (GDM). Therefore, our objective was to explore the relationship between AIP and GDM and assess AIP's predictive capability for GDM.

Methods

This was a secondary analysis based on data from a prospective cohort study in Korea involving 585 single pregnant women. AIP was calculated as log10 (TG/HDL). We examined the relationship between AIP and GDM using logistic regression models, curve fitting, sensitivity analyses, and subgroup analyses. Receiver opera

SUBMITTER: Zhang J 

PROVIDER: S-EPMC11227226 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature