Long-term outcomes of CNS WHO grade 2 oligodendroglioma in adult patients: a single-institution experience.

ABSTRACT:

Purpose

Oligodendrogliomas (ODGs) are a subtype of diffuse lower-grade gliomas with overall survival of > 10 years. This study aims to analyze long-term outcomes and identify prognostic factors in patients with WHO grade 2 ODG.

Methods

We retrospectively reviewed 138 adult patients diagnosed with 1p/19q co-deleted ODG who underwent surgical resection or biopsy between 1994 and 2021, analyzing clinical data, treatment details, and outcomes. Progression-free survival (PFS) and overall survival (OS) were evaluated using Kaplan-Meier analysis. Univariate and multivariate Cox regression analyses were utilized to identify significant prognostic factors.

Results

In the gross total resection (GTR) group, 63 (45.7%) underwent observation and 5 (3.6%) received postoperative tre

SUBMITTER: Byeon Y 

PROVIDER: S-EPMC11227491 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature