Associations between systemic inflammation indicators and nonalcoholic fatty liver disease: evidence from a prospective study.

ABSTRACT:

Background

Although inflammation has been linked to nonalcoholic fatty liver disease (NAFLD), most studies have focused only on a single indicator, leading to inconsistent results. Therefore, a large prospective study that includes a variety of well-documented single and composite indicators of inflammation is needed. This study aimed to thoroughly investigate the potential associations between different systemic inflammatory indicators and NAFLD in the UK Biobank cohort.

Methods

After excluding ineligible participants, 378,139 individuals were included in the study. Associations between systemic inflammatory indicators and hepatic steatosis were assessed using multivariate logistic regression. The relationships between systemic inflammatory indicators and nonalcoholic fatty

SUBMITTER: Gong H 

PROVIDER: S-EPMC11228160 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature