The association between vitamin D and the progression of diabetic nephropathy: insights into potential mechanisms.

ABSTRACT:

Aims

Vitamin D deficiency (VDD) is prevalent in the population, with inadequate intake, impaired absorption and metabolism as the main causative factors. VDD increases the risk of developing chronic diseases such as type 2 diabetes mellitus (T2DM) and diabetic nephropathy (DN), but the molecular mechanisms underlying this phenomenon are not known. The aim of this study was to investigate the association and potential mechanisms of vitamin D levels with the progression of DN by analyzing general clinical data and using bioinformatics methods.

Methods

The study included 567 diabetes mellitus type 2 (T2DM) patients from the Rocket Force Characteristic Medical Center as the case group and 221 healthy examinees as the normal control group. T2DM patients were categorized into T2DM

SUBMITTER: Gao J 

PROVIDER: S-EPMC11228314 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature