The interplay between temperature and growth phase shapes the transcriptional landscape of <i>Pseudomonas aeruginosa</i>.

ABSTRACT: Pseudomonas aeruginosa is a highly versatile bacterium capable of surviving and often thriving in stressful environmental conditions. Here we report the effect of two environmental conditions, temperature and growth phase, on the P. aeruginosa PAO1 transcriptome. As P. aeruginosa is well-known for its growth phase dependent phenotypes and gene regulation, our goal was to determine how temperature altered global gene expression at exponential versus stationary phase and to characterize how growth phase affects thermoregulation. To do this, we grew PAO1 in parallel at 25°C and 37°C and sampled the same populations first at exponential phase and then again at stationary phase and assessed gene expression by RNA-sequencing. We found that temperature regulated hundreds of g

SUBMITTER: Robinson RE 

PROVIDER: S-EPMC11230357 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature