Association between thyroid function and nonalcoholic fatty liver disease: a dose-response meta-analysis.

ABSTRACT:

Background

Thyroid hormones (THs) have been found that it is closely associated with the onset and progression of non-alcoholic fatty liver disease (NAFLD). However, the current study could not verify the intrinsic relationship between thyroid hormones and NAFLD, which requires further research.

Methods

The searches of studies reported both TH level in serum and NAFLD were performed in PubMed, Web of Science, Cochrane Library, and Embase databases. We combined an overall meta-analysis with a dose-response meta-analysis to assess the correlation and dose-response relationship between thyroid function levels and the risk of NAFLD.

Results

Overall, 10 studies were included with a total of 38,425 individuals. We found that the non-linear dose-response model showed that fo

SUBMITTER: Xiang LL 

PROVIDER: S-EPMC11231071 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature