The prognostic value of immune escape-related genes in lung adenocarcinoma.

ABSTRACT:

Background

Lung cancer is one of the most common cancers in humans, and lung adenocarcinoma (LUAD) has become the most common histological type of lung cancer. Immune escape promotes progression of LUAD from the early to metastatic late stages and is one of the main obstacles to improving clinical outcomes for immunotherapy targeting immune detection points. Our study aims to explore the immune escape related genes that are abnormally expressed in lung adenocarcinoma, providing assistance in predicting the prognosis of lung adenocarcinoma and targeted.

Methods

RNA data and related clinical details of patients with LUAD were obtained from The Cancer Genome Atlas (TCGA) database. Through weighted gene coexpression network analysis (WGCNA), 3112 key genes were screened and inte

SUBMITTER: Jia HR 

PROVIDER: S-EPMC11231773 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature