Comparing laparoscopic and open resection in elderly hepatocellular carcinoma: a systematic review and meta-analysis.

ABSTRACT:

Background

Laparoscopic liver resection (LLR) has been accepted as a safe and effective treatment for hepatocellular carcinoma (HCC). However, its impact on elderly patients remains uncertain. This study aimed to compare the efficacy and safety of LLR with open liver resection (OLR) in elderly HCC patients.

Methods

We conducted a search across the Ovid-Medline, Ovid-EMBASE, and Cochrane Library to identify comparative studies involving primary HCC in elderly patients (≥65 years). Efficacy-related outcomes encompassed overall survival (OS) and disease-free survival (DFS), while safety-related outcomes included post-operative mortality, complications, and length of stay (LOS).

Results

We identified nine eligible cohort studies comprising 1,599 patients. LLR demonstrated

SUBMITTER: Yoo JJ 

PROVIDER: S-EPMC11231836 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature