RepurposeDrugs: an interactive web-portal and predictive platform for repurposing mono- and combination therapies.

ABSTRACT: RepurposeDrugs (https://repurposedrugs.org/) is a comprehensive web-portal that combines a unique drug indication database with a machine learning (ML) predictor to discover new drug-indication associations for approved as well as investigational mono and combination therapies. The platform provides detailed information on treatment status, disease indications and clinical trials across 25 indication categories, including neoplasms and cardiovascular conditions. The current version comprises 4314 compounds (approved, terminated or investigational) and 161 drug combinations linked to 1756 indications/conditions, totaling 28 148 drug-disease pairs. By leveraging data on both approved and failed indications, RepurposeDrugs provides ML-based predictions for the approval potential of new drug-d

SUBMITTER: Ianevski A 

PROVIDER: S-EPMC11232279 | biostudies-literature | 2024 May

REPOSITORIES: biostudies-literature