Genotyping-by-sequencing targets genic regions and improves resolution of genome-wide association studies in autotetraploid potato.

ABSTRACT:

Key message

De novo genotyping in potato using methylation-sensitive GBS discovers SNPs largely confined to genic or gene-associated regions and displays enhanced effectiveness in estimating LD decay rates, population structure and detecting GWAS associations over 'fixed' SNP genotyping platform. Study also reports the genetic architectures including robust sequence-tagged marker-trait associations for sixteen important potato traits potentially carrying higher transferability across a wider range of germplasm. This study deploys recent advancements in polyploid analytical approaches to perform complex trait analyses in cultivated tetraploid potato. The study employs a 'fixed' SNP Infinium array platform and a 'flexible and open' genome complexity reduction-based sequencing method

SUBMITTER: Sharma SK 

PROVIDER: S-EPMC11233353 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature