Prevalence and epidemiology of stroke in patients with multiple sclerosis: a systematic review and meta-analysis.

ABSTRACT:

Background

Epidemiological data are sparse regarding the risk of stroke in patients with multiple sclerosis (MS).

Objective

To estimate the following: (1) the pooled prevalence of all-cause stroke, acute ischaemic stroke (AIS) and intracerebral haemorrhage (ICH) in MS patients; (2) the relative risk for all-cause stroke, AIS and ICH in MS patients compared to the general population; (3) associations between patient characteristics and the risk for AIS and ICH in MS patients.

Methods

Systematic review and meta-analysis of registry-based and cohort studies.

Results

Thirteen observational studies comprising 146,381 MS patients were included. The pooled prevalence of all-cause stroke was 2.7% (95% confidence interval [CI] 1.3-4.6%), with the relative risk of all-ca

SUBMITTER: Stefanou MI 

PROVIDER: S-EPMC11233381 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature