The mouse multi-organ proteome from infancy to adulthood.
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ABSTRACT:
SUBMITTER: Wang Q
PROVIDER: S-EPMC11233712 | biostudies-literature | 2024 Jul
REPOSITORIES: biostudies-literature
Publications
The mouse multi-organ proteome from infancy to adulthood.
Wang Qingwen Q Ding Xinwen X Xu Zhixiao Z Wang Boqian B Wang Aiting A Wang Liping L Ding Yi Y Song Sunfengda S Chen Youming Y Zhang Shuang S Jiang Lai L Ding Xianting X
Nature communications 20240709 1
The early-life organ development and maturation shape the fundamental blueprint for later-life phenotype. However, a multi-organ proteome atlas from infancy to adulthood is currently not available. Herein, we present a comprehensive proteomic analysis of ten mouse organs (brain, heart, lung, liver, kidney, spleen, stomach, intestine, muscle and skin) at three crucial developmental stages (1-, 4- and 8-weeks after birth) acquired using data-independent acquisition mass spectrometry. We detect and ...[more]
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