Ischemic Stroke After Bivalent COVID-19 Vaccination: Self-Controlled Case Series Study.

ABSTRACT:

Background

The potential association between bivalent COVID-19 vaccination and ischemic stroke remains uncertain, despite several studies conducted thus far.

Objective

This study aimed to evaluate the risk of ischemic stroke following bivalent COVID-19 vaccination during the 2022-2023 season.

Methods

A self-controlled case series study was conducted among members aged 12 years and older who experienced ischemic stroke between September 1, 2022, and March 31, 2023, in a large health care system. Ischemic strokes were identified using International Classification of Diseases, Tenth Revision codes in emergency departments and inpatient settings. Exposures were Pfizer-BioNTech or Moderna bivalent COVID-19 vaccination. Risk intervals were prespecified as 1-21 days and 1-42

SUBMITTER: Xu S 

PROVIDER: S-EPMC11234065 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature