Bone Pain and Survival Among Patients With Metastatic, Hormone-Sensitive Prostate Cancer: A Secondary Analysis of the SWOG-1216 Trial.

ABSTRACT:

Importance

The presence of bone pain is significantly associated with worse overall survival (OS) in patients with castration-resistant prostate cancer. However, there are few data regarding bone pain and survival outcomes in the context of metastatic, hormone-sensitive prostate cancer (MHSPC).

Objective

To compare survival outcomes among patients with MHSPC by presence or absence of baseline bone pain at diagnosis.

Design, setting, and participants

This post hoc secondary analysis, conducted from September 1 to December 31, 2023, used patient-level data from SWOG-1216, a phase 3, prospective randomized clinical trial that enrolled patients with newly diagnosed MHSPC from 248 academic and community centers across the US from March 1, 2013, to July 15, 2017. All patien

SUBMITTER: Gebrael G 

PROVIDER: S-EPMC11234233 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature