A systematic review of the drug-drug interaction between Statins and Quinolones.

ABSTRACT:

Background

Statins are widely used in cardiovascular disease (CVD) as a common lipid-lowering drug, while quinolones are widely used for the treatment of infectious diseases. It is common to see CVD in combination with infectious diseases, therefore it is often the case that statins and quinolones are used in combination. Data suggest combinations of statin and quinolone may be associated with potentially life-threatening myopathy, rhabdomyolysis and acute hepatitis. This systematic review aims to characterize data regarding patients affected by the statin-quinolone interaction.

Methods

The purpose of this systematic review was to collect and evaluate the evidence surrounding statin-quinolone drug interactions and to discuss related risk mitigation strategies. The following

SUBMITTER: Zhou J 

PROVIDER: S-EPMC11234672 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature