The relationship between uric acid and bone mineral density in the intermediate stage of CKD 1-3.

ABSTRACT:

Background

Some studies have suggested that uric acid has antioxidant properties that can prevent bone loss, but the relationship between uric acid and bone mineral density is controversial. The aim of this study was to investigate the relationship between UA and BMD in patients with CKD stage 1-3.

Methods

We extracted 13,047 participants from the NHANES database, including 7342 male subjects and 5705 female subjects. Weighted multiple linear regression analysis was used to investigate the correlation between UA and BMD in patients with CKD stages 1-3.

Results

In patients with CKD stage 1-3, UA was significantly correlated with BMD. In the male group, UA was positively associated with BMD (β, 7.94 [95%CI, 4.95, 10.94]). In the female group, there was a negative relati

SUBMITTER: Yang R 

PROVIDER: S-EPMC11234712 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature