ProcaryaSV: structural variation detection pipeline for bacterial genomes using short-read sequencing.

ABSTRACT:

Background

Structural variations play an important role in bacterial genomes. They can mediate genome adaptation quickly in response to the external environment and thus can also play a role in antibiotic resistance. The detection of structural variations in bacteria is challenging, and the recognition of even small rearrangements can be important. Even though most detection tools are aimed at and benchmarked on eukaryotic genomes, they can also be used on prokaryotic genomes. The key features of detection are the ability to detect small rearrangements and support haploid genomes. Because of the limiting performance of a single detection tool, combining the detection abilities of multiple tools can lead to more robust results. There are already available workflows for structural va

SUBMITTER: Jugas R 

PROVIDER: S-EPMC11234778 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature